A study examining the correlation between error-related negativity and the severity of generalized anxiety disorder symptoms.
Extract
[...] Increased error-related brain activity in generalized anxiety disorder - Anna Weinberg, Doreen M. Olvet, Greg Hajcak (2010) The authors studied the role of the anterior cingulate cortex activated by error-related negativity in generalized anxiety disorder (GAD). No study to date has examined error-related brain activity in individuals with GAD. This study also examined the differentiation between ERN and correct response negativity (CRN). The authors hypothesized that error processing would be more pronounced in individuals with GAD than in healthy controls, and that the magnitude of error-related negativity could be correlated with the severity of symptoms in individuals with GAD. [...]
[...] Consistent with the hypotheses, error-related brain activity is more pronounced in individuals with GAD than in healthy controls, and no significant difference in behavioral measures is observed. This is in line with the implication of the ACC, as a generator of ERN, in the pathophysiology of GAD. In this study, patients with GAD on medication were excluded, although they are numerous in the global population to have recourse to them. Also, even if patients with GAD did not have comorbidity at the time of the study, the questionnaires showed a history of depression. [...]
