Vitamin D, Vitamin K, cardiovascular health, vascular calcification, mortality risk, nutritional supplements, heart disease risk factors, cardiovascular disease prevention, adults
Discover the synergistic benefits of vitamins D and K in maintaining cardiovascular health and preventing vascular calcification. Research shows that combined supplementation may reduce mortality risk and support overall well-being. Learn how these essential vitamins work together to activate proteins that inhibit calcification and promote bone health. Understand the recommended intakes and potential benefits of co-supplementation for adults, particularly in preventing cardiovascular diseases and managing type 2 diabetes.
[...] J. (2020b). The Association of Vitamin D and Vitamin K Status with Subclinical Measures of Cardiovascular Health and All-Cause Mortality in Older Adults: The Hoorn Study. The Journal of Nutrition/The Journal of Nutrition, 150(12), 3171-3179. https://doi.org/10.1093/jn/nxaa293 49. Amrein, K., Scherkl, M., Hoffmann, M. et al. Vitamin D deficiency 2.0: an update on the current status worldwide. Eur J Clin Nutr 74, 1498-1513 (2020). https://doi.org/10.1038/s41430-020-0558-y 50. ANSES. Nutritional references for vitamins and minerals April 23. [...]
[...] https://doi.org/10.1007/s00394-020-02352-8 14. Van Ballegooijen, A. J., Cepelis, A., Visser, M., Brouwer, I. A., Van Schoor, N. M., & Beulens, J. W. (2017). Joint Association of Low Vitamin D and Vitamin K Status with Blood Pressure and Hypertension. Hypertension, 1165-1172. https://doi.org/10.1161/hypertensionaha.116.08869 15. Haute Autorité de Santé. Note de Cadrage. [...]
[...] When long-term observational studies conducted on populations reveal health effects, such as disease prevention, they are considered to define a SI. To estimate nutritional status, data come from observational or experimental studies. The ANSES specifies that the upper limit of safety (ULS) corresponds to "thethe chronic daily intake of a vitamin or mineral considered to be unlikely to pose a risk of adverse health effects for the entire population [50]. 5.1.2 Recommended intakes of vitamins K1 and K2 The recommended daily intakes of VK1 and VK2 vary by age. [...]
[...] It alters the arterial walls and the risk of IDM is further increased in the case of passive smoking [17]. - Diabetes Diabetes is diagnosed when 'blood glucose is greater than 1.26 g/l on an empty stomach during two blood tests.' If not treated, the arterial walls can be altered by hyperglycemia. In addition, in a diabetic person, the kidneys overwork to filter the blood and reduce blood glucose. This organ can then be affected prematurely. Albumin can then be measured in the urine (microalbuminuria) [17]. [...]
[...] (2022b). Serum Homocysteine and Vascular Calcification: Advances in Mechanisms, Related Diseases, and Nutrition. Korean Journal of Family Medicine, 277-289. https://doi.org/10.4082/kjfm.21.0227 42. Bartstra, J. W., Draaisma, F., Zwakenberg, S. R., Lessmann, N., Wolterink, J. M., Van Der Schouw, Y. T., De Jong, P. A., & Beulens, J. W. J. [...]
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